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Overview
Pharmacology
The Department of Pharmacology was started in 1964, under the first head Dr. Aiman and is committed to high quality educational, research and service activities. Currently, our department provides quality education in Pharmacology and therapeutics for undergraduate and post graduate Medical, undergraduate Nursing and also for Allied health sciences students. Emphasis is placed to provide knowledge and skills required for rational, effective and safe use of drug therapy which make them competent health care professionals. Since 2008, the MBBS curriculum has incorporated applied pharmacology sessions as well as seminars and quizzes. The practical training curriculum has been recently updated to focus on clinical applications and basics of therapeutics.
The post graduate program (MD) was established in 1992 and the PhD program was started in 1989. We have implemented a well structured post graduate teaching program which includes external postings in the pharma industry, Bioequivalence unit, division of clinical research and training at St .John's research Institute and other institutions like CMC Vellore and NIMHANS. Till date, we have trained 60 MD students and 5 PhD students. Currently, we have grown to become one of the leading Pharmacology departments in the country.
The faculty of the Department are actively involved in quality multicentre research projects of national and international importance. Focus of research in the initial years was on preclinical studies in asthma, epilepsy and phase I studies but now the focus is on large multicentre projects on prevention and treatments of Non Communicable Diseases (NCDs). We have also developed a video to train clinical researchers on the constitution and functioning of Institutional Ethics Committees (IEC).
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Patient and caregiver reported facilitators of self-care among patients with chronic heart failure: report from a formative qualitative study
One-year outcomes after discharge from noncardiac surgery and association between pre-discharge complications and death after discharge: analysis of the VISION prospective cohort study
One-year Results of a Factorial Randomised Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery
Effect of dulaglutide on cognitive impairment in type 2 diabetes: an exploratory analysis of the REWIND trial
Medication errors in neonatal intensive care unit of a tertiary care hospital in South India: A prospective observational study
Polypill with or without Aspirin in Persons without Cardiovascular Disease
Situational Analysis of Practice Patterns and Challenges in Cardiovascular Disease Management - Qualitative Study
Health and economic impact of air pollution in the states of India: the Global Burden of Disease Study 2019
A qualitative, grounded theory exploration of the determinants of self-care behavior among Indian patients with a lived experience of chronic heart failure
The burden of neurological disorders across the states of India: the Global Burden of Disease Study 1990–2019
Erectile function in men with type 2 diabetes treated with dulaglutide: an exploratory analysis of the REWIND placebo-controlled randomised trial
Three weeks compared to seven-week run-in period length and the assessment of pre-randomization adherence: A study within a trial
Variations in knowledge, awareness and treatment of hypertension and stroke risk by country income level
Urinary Sodium and Potassium, and Risk of Ischemic and Hemorrhagic Stroke (INTERSTROKE): A Case-Control Study
Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation
Lowering cholesterol, blood pressure, or both to prevent cardiovascular events: results of 8.7 years of follow-up of Heart Outcomes Evaluation Prevention (HOPE)-3 study
The role and challenges of cluster randomised trials for global health
Randomised trials at the individual level
Urgently seeking efficiency and sustainability of clinical trials in global health
Safety of hydroxychloroquine in healthcare workers for COVID-19 prophylaxis
Efficacy and Safety of Dulaglutide in Older Patients: A post hoc Analysis of the REWIND trial
Prevalence of modifiable cardiovascular risk factors among coffee estate workers in rural South India (CARE)
The utility of Vibratip in accurate identification of loss of protective sensation in the contralateral foot of patients admitted with a diabetic foot ulcer
Hydroxychloroquine for SARS CoV2 Prophylaxis in Healthcare Workers – A Multicentric Cohort Study Assessing Effectiveness and Safety
The Cost Implications of Dabigatran in Patients with Myocardial Injury After Non-Cardiac Surgery
Measurement of hydroxychloroquine (hcq) in blood in asymptomatic healthcare workers on prophylactic regimen for covid-19 infection - an observational study
Use and adherence to oral anticoagulants in a tertiary care hospital
Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis
Topical Controlled Warm Oxygen Therapy Delivered Through a Novel Device (KADAM™) to Treat Diabetic Foot Ulcers: A Randomised Controlled, Open, Pilot Trial
Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study
Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomised Clinical Trial
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomised controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery
HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial
Predictors of Pharmacotherapy and Quality of Life Among Patients With Diabetic Foot Syndrome: A Cross-Sectional Study from a Tertiary Care Hospital in India
The Anti-Coronavirus Therapies (ACT)
Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE)
Tranexamic acid in patients undergoing noncardiac surgery
Effects of aspirin in primary prevention of cardiovascular disease in people with chronic kidney disease: results of the TIPS3 trial
Role of Proxy Respondents in International Stroke Research: Experience of the INTERSTROKE Study
Meeting sustainable development goals via robotics and autonomous systems
Usability and feasibility assessment of a smartphone application (Suhriday) for heart failure self-care remote monitoring in an Indian tertiary health care setting: a pilot mixed-methods study
Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial
A novel kidney disease index reflecting both the albumin-to-creatinine ratio and estimated glomerular filtration rate predicted cardiovascular and kidney outcomes in type 2 diabetes
Use of Mobile Phones in Patients with Stroke
The Cost Implications of a Polypill for Primary Prevention in the TIPS-3 Trial
Association of Psychosocial Stress With Risk of Acute Stroke
Patterns of Drug Use and Adverse Drug Reactions in Patients with Autoimmune Bullous Disease (AIBD).
Quality of Life in Patients with Autoimmune Bullous Disease (AIBD).
Alcohol Intake as a Risk Factor for Acute Stroke: The INTERSTROKE Study
Patterns of medication use and their determinants in pregnancy among women admitted to the obstetrics ward of a tertiary care hospital: A cross sectional study
Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA): a multicentre, randomised controlled trial
Effects of a polypill, aspirin or both on cognitive and functional outcomes. A randomised clinical trial
Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease
Vitamin D supplementation and adverse skeletal and non-skeletal outcomes in individuals at increased cardiovascular risk: Results from the International Polycap Study (TIPS)-3
Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study
Strategies for Promoting Research among Endocrinologists in Private Practice
Sleep Patterns and the Risk of Acute Stroke: Results from the INTERSTROKE International Case-Control Study
Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery: An International Randomised Controlled Trial
Characteristics, clinical practice patterns and outcomes of strokes in India: INSPIRE-A multicentre prospective study
An Observational Multi-centric COVID-19 Sequelae Study among Health Care Workers
A randomised controlled trial evaluating a theory-driven, complex intervention centred on task sharing and mobile health to improve self-care and outcomes in heart failure
Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised Trials
Variations in the prevalence of atrial fibrillation, and in the strength of its association with ischemic stroke, in countries with different income levels: INTERSTROKE case-control study
One-year outcomes after discharge from noncardiac surgery and association between pre-discharge complications and death after discharge: analysis of the VISION prospective cohort study
Tobacco use and risk of acute stroke in 32 countries in the INTERSTROKE study: a case-control study
Pre-morbid sleep disturbance and its association with stroke severity: results from the international INTERSTROKE study
Blood pressure variability in acute stroke: Risk factors and association with functional outcomes at 1 month
Cost-effectiveness analysis of a fixed dose combination pill for primary prevention of cardiovascular disease from an individual participant data meta-analysis
Markers of Periodontal Disease and risk of Stroke: INTERSTROKE case-control study
Tea and coffee consumption and risk of acute stroke: The INTERSTROKE Study
A sub-study of the POISE-3 randomised trial examined the effects of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury
Carbonated Beverage, Fruit Drink, and Water Consumption and Risk of Acute Stroke: the INTERSTROKE Case-Control Study
Association of Vascular Risk With Severe vs Non-Severe Stroke: An Analysis of the INTERSTROKE Study
Using Preoperative Race-Free Estimated GFR to Predict Cardiac Events in Major Noncardiac Surgery: Secondary Analysis of Two Large International Studies
Safety and efficacy of tranexamic acid in general surgery
Preoperative estimated glomerular filtration rate to predict cardiac events in major noncardiac surgery: a secondary analysis of two large international studies
Improving the clinical trial environment and infrastructure: moving from global resolution to action
District Residency Programme: Experience of a pharmacology resident
Influence of age on the association of vascular risk factors with acute stroke (INTERSTROKE): a case–control study
Effects of a hypotension-avoidance versus a hypertension-avoidance strategy on neurocognitive outcomes after noncardiac surgery
The Aldosterone Blockade for Health Improvement Evaluation in End-Stage Renal Disease (ACHIEVE) Trial: Rationale and Clinical Research Protocol
Prescribing trends of fixed-dose combination of domperidone and proton-pump inhibitor across tertiary care centers in India, is the combination rational?
A critical evaluation of available explicit deprescribing tools for their applicability to Indian elderly patients: a scoping review protocol.
Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial.
A Drug Utilisation study of antihypertensives and anti-diabetics in a tertiary care hospital.
Pattern of Drug Use in Hypertension in a Tertiary Hospital: A Cross-Sectional Study in the In-Patient Wards
Pharmacology of anti-epileptic drugs: A computer-aided teaching module and its evaluation in medical undergraduates
Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction
Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction
Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomised controlled trial
Effects of reviparin, a low-molecular-weight heparin, on mortality, reinfarction, and strokes in patients with acute myocardial infarction presenting with ST-segment elevation
Rationale, design, and organisation of the PeriOperative Ischemic Evaluation (POISE) trial: a randomised controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery
VITATOPS, the VITAmins TO prevent stroke trial: rationale and design of a randomised trial of B-Vitamin therapy in patients with recent transient ischemic attack or stroke
Perspectives on the management of coronary artery disease in India
Effects of Fondaparinux in patients with ST-segment elevation acute myocardial infarction not receiving reperfusion treatment
Glucose-insulin-potassium (GIK) therapy in patients with ST-segment elevation myocardial infarction: Results of the OASIS-6-GIK trial and the combined analyses of the OASIS-6 and the CREATE-ECLA GIK trials
Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data
Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial
The need to test the theories behind the Polypill: the rationale behind the Indian Polycap Study
Polypharmacotherapy for Primary Prevention of Cardiovascular Disease
Effects of a polypill (polycap) on risk factors in middle-aged individuals without cardiovascular disease (tips): A phase II, double-blind, randomised trial
Dabigatran versus warfarin in patients with atrial fibrillation
Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke
Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study
Low-Dose vs Standard-Dose Unfractionated Heparin for The Percutaneous Coronary Percutaneous Coronary Intervention in Acute Coronary Syndromes Treated With Fondaparinux: The FUTURA/OASIS-8 Randomised Trial
Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial.
The polypill in the prevention of cardiovascular diseases. Key concepts, current status, challenges, and future directions
Prevalence, risk factors, manifestations, treatments and outcomes of coronary artery disease in Indians: a systematic review
Translating evidence into policy for cardiovascular disease control in India
Prevalence, risk factors, manifestations, treatments and outcomes of coronary artery disease in Indians: a systematic review
Characteristics and Short-Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery: A Cohort Study
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