Publications
Effects of a polypill (polycap) on risk factors in middle-aged individuals without cardiovascular disease (tips): A phase II, double-blind, randomised trial
Yusuf S, Pais P, Afzal R, Xavier D, Teo K, Eikelboom J, et al. Background
The combination of three blood-pressure-lowering drugs at low doses, with a statin, aspirin, and folic acid (the polypill), could reduce cardiovascular events by more than 80% in healthy individuals. We examined the effect of the Polycap on blood pressure, lipids, heart rate, and urinary thromboxane B2, and assessed its tolerability.
