faculty

Publications

Effects of a hypotension-avoidance versus a hypertension-avoidance strategy on neurocognitive outcomes after noncardiac surgery

Groups and Associations Maura Marcucci, Matthew TV Chan, Thomas W Painter, … Denis Xavier, Edith Fleischmann, Chew Yin Wang, Christian S Meyhoff, …PJ Devereaux
Annals of Internal Medicine 2025

Abstract

Background:

Perioperative hemodynamic abnormalities have been associated with neurocognitive outcomes after noncardiac surgery.

Objective:

To compare the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery.

Design:

Randomized controlled trial. (ClinicalTrials.gov: NCT03505723)