Radiation Oncology (Radiotherapy)

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Overview

Anatomy

The Department of Radiation Oncology, located on the ground floor of the St. John’s Oncology Centre (St. John’s Medical College Hospital, closest access through Gate No. 2, Sarjapur Road), commenced its operations in January 2013. We offer expertise and facilities dedicated to providing high-quality and high-precision treatments

The department is equipped with state-of-the-art technology, including a high-end Linear Accelerator (Elekta® Agility) and the Monaco treatment planning system (TPS) for external beam radiotherapy, both recently upgraded in the year 2023, along with a High Dose Rate (HDR) Brachytherapy unit from Eckert Zeigler® (HDR Multi source Brachytherapy unit).

Our department delivers a full spectrum of advanced radiotherapy, from 3DCRT and IMRT to high-precision IGRT and VMAT. We specialize in ultra-targeted treatments including SRS/SRT and SBRT, as well as complex, life-saving procedures such as Total Body Irradiation (TBI) for bone marrow transplants and Total Skin Electron Therapy (TSET) for cutaneous lymphomas.

The department has treated over 5,000 patients with external beam radiotherapy on the linear accelerator and conducted over 1,500 sessions of brachytherapy through December 2025.

Furthermore, we demonstrate our commitment to academic excellence by running the BSc Radiotherapy Technologist course since the year 2018 and MD Radiation Oncology course since the year 2020. Our MD and the BSc Courses are affiliated with Rajiv Gandhi University of Health Sciences, Bengaluru. The MD course is recognised by the National Medical Commission (NMC), and the BSc course is recognised by the Atomic Energy Regulatory Board (AERB).

Our department is dedicated to shaping the next generation of Radiation Therapy Physicians and Technologists through a curriculum rooted in systematic learning and reinforced by intensive practical exposure. We believe that a true master of radiotherapy must not only understand the physics of the beam but also the humanity of the patient sitting beneath it.

Our Team

Lead

Most Rev. Prakash Mallavarapu
Professor and Head

Professor and Head, Department of Radiation Oncology

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Core Staff

Most Rev. Prakash Mallavarapu
Professor

MBBS,MD Radiotherapy

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Most Rev. Prakash Mallavarapu
Assistant Professor

MBBS, MD,DNB Radiation Oncology

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Most Rev. Prakash Mallavarapu
Senior Resident

MBBS,MD Radiation Oncology

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Most Rev. Prakash Mallavarapu
Senior Resident

Senior Resident,Department of Radiation Oncology

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Services

Anatomy

Advanced External Beam Radiotherapy

We are equipped to deliver highly precise treatments such as Intensity Modulated Radiotherapy (IMRT), Image Guided Radiotherapy (IGRT), Volumetric Modulated Arc Therapy (VMAT), Stereotactic Body Radiotherapy (SBRT), Stereotactic Radiotherapy (SRT) and Stereotactic Radiosurgery (SRS). We also are equipped to treat patients with 2D Conventional, 3DCRT and Electron beam therapy when its essential. 

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Anatomy

Total Body Irradiation (TBI) and Craniospinal Irradiation (CSI)

Total Body Irradiation (TBI) is a specialized form of radiation therapy that involves treating the entire body with a uniform dose of radiation. It’s most commonly used as a "conditioning" treatment before a bone marrow transplant or stem cell transplant.Craniospinal Irradiation (CSI) is a technique where the Radiation is delivered to entire craniospinal access, for specific indications such as Medulloblastoma. 

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Anatomy

Total Skin Electron Therapy (TSET)

TSET is a highly complex treatment that involves delivering electron beam therapy to the entire skin surface of the body. This procedure requires stringent quality assurance by the Medical Physics team and meticulous customization for each patient. It is used in the treatment of cutaneous lymphoma (Ex: Mycosis Fungoides) 

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Anatomy

Radiotherapy under Anaesthesia

Paediatric patients with cancer and agitated patients requiring Radiotherapy are treated under Anaesthesia. 

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Anatomy

Brachytherapy

Brachytherapy is placement of sealed radioactive sources in close proximity to the tumor and target tissue. We offer Intracavitary (ICBT), Interstitial (ISBT), Intraluminal (ILBT), and Surface Mould Brachytherapy (SMBT). 

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Projects

S.I. No Project Title Project Lead Project Type Year of Initiation Status
1 Pain management and analgesic strategies in patients with carcinoma uterine cervix undergoing intracavitary or interstitial brachytherapy Sakshi Retrospective 2025 completed
2 Herpetic Reactivation in Radiotherapy treatment of Gynaecological Cancers- A Retrospective Observational Study Deepu C Tom Retrospective Observational Study 2024 completed
3 Limited pelvic radiotherapy in postoperative Carcinoma Uterine Cervix and Endometrium. A retrospective study. Hadrian Noel Alexander Retrospective cohort study 2024 completed
4 Comparison of different patient positioning and immobilization techniques for pelvic malignancies. Avinash H Udayashankara Retrospective cohort study 2016 completed
5 Correlation of dose to pelvic bone and decline in bone mineral density using computed tomography in patients of carcinoma cervix treated with definitive chemoradiation Jayalekshmi R Retrospective Observational Study 2024 completed
6 Definitive Radiotherapy in Node positive Carcinoma Uterine Cervix: A single Institution experience. Hadrian Noel Alexander Retrospective cohort study 2022 completed
7 Identification and evaluation of prognostic markers involving Rho/ROCK signaling pathway in radiation response in cervical cancer. Sweta Srivastava Prospective (Funded by RGUHS) 2018 completed
8 Hypofractionation versus conventional fractionation in breast conservation surgery: a prospective observational study Nirmala S Prospective Observational Study 2017 completed
9 ROCK2 dependant radiation induced DNA repair in cervical carcinoma - A translational opportunity Sweta Srivastava Prospective (Funded DBT Biocare) 2017 completed
10 Pattern of RNA based blood biomarkers in squamous cell carcinoma cervix treated with definitive Radiotherapy: A pilot Study Avinash H Udayashankara Prospective Observational Study 2017 completed
11 Clinical Outcome and Pathologic Response after Neo-Adjuvant Chemoradiation in locally advanced Rectal Cancers – A Prospective and Retrospective Observational Study Avinash H Udayashankara Prospective 2017 completed
12 Role of RhoC in regulation of Cancer Stem Cells Sweta Srivastava Prospective (Funded by SERB - DST) 2017 completed
13 Volumetric image guided Intravaginal Brachytherapy – A retrospective dosimetric and clinical study. Avinash H Udayashankara Retrospective cohort study 2017 completed
14 Radiation induced brachial plexopathy in Head and Neck cancer patients treated with Definitive Radiotherapy and correlation with disease characteristics and dosimetric parameters F Hadrian Noel Alexander Retrospective Cohort Study 2020 completed
15 Sepsis surveillance in patients with head-and-neck cancer undergoing chemo-radiation Ajay Babu Retrosective Cohort Study 2022 completed
16 Trends in radiation therapy administration at a pediatric cancer center in South India Sakshi Garg Retrospective Cohort Study 2025 completed
17 Dose-Volume Predictors for Radiation induced Esophagitis in Patients With Breast Cancer Undergoing Supraclavicular Irradiation F Hadrian Noel Alexander Retrospective Cohort Study 2025 ongoing
18 Corelation between 18-FDG PETCT quantitative parameters with clinicopathological features and survival outcomes in head and neck squamous cell carcinomas F Hadrian Noel Alexander Retrospective Cohort Study 2025 ongoing

Publications

Limited pelvic radiotherapy in post-operative uterine carcinoma

Groups and Associations Hadrian Noel Alexander, Avinash H Udayashankara, Silpa Johnson, Nirmala Srikantia, John Michael Raj
Reports of Practical Oncology and Radiotherapy 2025
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Clinicopathological Characteristics and Outcomes of Metaplastic Breast Cancer: Experience from a Tertiary Cancer Center in India

Groups and Associations Vijaya L. V. Venkata,Donna C. P. Tharappel, Ganesha D. Vashishta, Rakesh S. Ramesh, Nirmala Srikantia, Akshai C. Kashiappa
Indian Journal of Medical and Paediatric Oncology 2025
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Trends in radiation therapy administration at a pediatric cancer center in South India

Groups and Associations Sakshi Garg, Sandeep Muzumder, Hadrian Noel Alexander F, Avinash H. Udayashankara, Nirmala Srikantia, John Michael Raj
Pediatric Hematology Oncology Journal 2025
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Predictive Factors for Esophageal Stricture Following Definitive Chemoradiotherapy in Esophageal Carcinoma

Groups and Associations Swathi R Krishna, Sandeep Muzumder, Silpa Johnson, Nirmala Srikantia, Avinash H U , Santu Ghosh, Rajesh Majumder
Journal of Gastrointestinal Cancer 2025
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Definitive radiotherapy with nodal boost for radiologically positive nodes in carcinoma cervix – A retrospective cohort study

Groups and Associations Alexander, F Hadrian Noel; Udayashankara, Avinash H.; Nirmala, S; Sebastian, M G John; Muzumder, Sandeep; Raju, Jayalekshmi; Tripathy, Arkaja; Ghosh, Santu
Journal of Cancer Research and Therapeutics 2024
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Evolving role of radiation therapy in paediatric cancer

Groups and Associations Sakshi Garg, Sandeep Muzumder, S. Nirmala, H.U. Avinash
Pediatric Hematology Oncology Journal 2024
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Sepsis surveillance in patients with head-and-neck cancer undergoing chemo-radiation

Groups and Associations Ajay Babu, Hadrian Noel Alexander F, Sandeep Muzumder, Nirmala Srikantia, Avinash H Udayashankar
Supportive Care in Cancer - Springer Nature 2024
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Radiation induced brachial plexopathy in head and neck cancer patients treated with definitive radiotherapy and correlation with disease characteristics and dosimetric parameters

Groups and Associations F Hadrian Noel Alexander, Nirmala Srikantia, Sandeep Muzumder, Avinash H Udayashankara, Mg John Sebastian, Deepu C Tom, R P Kathiressan, John Michael Raj
Reports of Practical Oncology and Radiotherapy 2024
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Aloe vera Alters Periostin Expression, Abolishes EMT Phenotype, and Sensitises Cells to Radiation in Conjunction With Atorvastatin in Cervical Cancer

Groups and Associations P. Thomas, S. Sahoo, S. Mahajan, D.L. Hiremath, A.H. Udayashankara, S. Srivastava
Journal of Herbal Medicine 2024
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Hospital factors determining overall survival in cancer patients undergoing curative treatment

Groups and Associations Sandeep Muzumder, Arkaja Tripathy, Hadrian N Alexander, Nirmala Srikantia
Journal of Cancer Research and Therapeutics 2024
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A comparison of conventional and accelerated hypofractionated radiotherapy in definitive chemoradiation for locally advanced head and neck carcinoma: a retrospective cohort study

Groups and Associations Arkaja Tripathy, Sandeep Muzumder, Nirmala Srikantia, Ajay Babu, Mg John Sebastian, Avinash H Udayashankar, Ganesha Dev Vashishta, John Michael Raj
Radiation Oncology Journal 2023
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RhoC in association with TET2/WDR5 regulates cancer stem cells by epigenetically modifying the expression of pluripotency genes

Groups and Associations Pavana Thomas, Sweta Srivastava, Avinash H Udayashankara, Samyuktha Damodaran, Lokendra Yadav, Boby Mathew, Srinag Bangalore Suresh, Amit Kumar Mandal, Nirmala Srikantia
Cellular and Molecular Life Sciences- Springer Nature 2022
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Volumetric image guidance for intravaginal brachytherapy: A dosimetric and clinical study

Groups and Associations Avinash H Udayashankara, Nirmala Srikantia, Sandeep Muzumder, Suparna H Chandramouli, John M Raj , Mazhar H Shariff
Journal of Cancer Research and Therapeutics 2022
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Late toxicities in locally advanced head and neck squamous cell carcinoma treated with intensity modulated radiation therapy

Groups and Associations Sandeep Muzumder, Nirmala Srikantia, Avinash H Udayashankar, Prashanth Bhat Kainthaje, M G John Sebastian, John Michael Raj
Radiation Oncology Journal 2021
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Burden of acute toxicities in head-and-neck radiation therapy: A single-institutional experience

Groups and Associations Sandeep Muzumder, Nirmala Srikantia, Avinash H Udayashankar, Prashanth Bhat Kainthaje, M G John Sebastian
South Asian Journal of Cancer Search Search filter 2020
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Optimal time management on linear accelerator: A logical model to reduce patient waiting time

Groups and Associations Avinash H Udayashankar, Shibina Noorjahan, Nirmala Srikantia, Ravindra Babu Kamunuri, Niranjan Immanuel, Sandeep Muzumder, S H Chandramouli, Mazhar H Shariff
Journal of Cancer Research and Therapeutics 2019
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RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancer

Groups and Associations Pranatharthi A, Thomas P, Udayashankar AH, Bhavani C, Suresh SB, Krishna S, Thatte J, Srikantia N, Ross
J Exp Clin Cancer Res 2019
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Early Competing Deaths in Locally Advanced Head-and-Neck Cancer

Groups and Associations Sandeep Muzumder, S Nirmala , HU Avinash , Prashanth Bhat Kainthaje , MG John Sebastian , John Michael Raj
Indian Journal of Palliative Care 2018
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Optimal technique of radiotherapy for carcinoma cervix in developing countries: Dosimetric and logistic comparison

Groups and Associations T R Arul Ponni , H U Avinash, S Nirmala, M G Janaki , A S Kirthi Koushik
Journal of Cancer Research and Therapeutics 2018
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Optimal time management on linear accelerator: A logical model to reduce patient waiting time

Groups and Associations Avinash H Udayashankar, Shibina Noorjahan, Nirmala Srikantia, Ravindra Babu Kamunuri, Niranjan Immanuel, Sandeep Muzumder, S H Chandramouli, Mazhar H Shariff
Journal of Cancer Research and Therapeutics 2019
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Compliance, toxicity and efficacy in weekly versus 3-weekly cisplatin concurrent chemoradiation in locally advanced head and neck cancer

Groups and Associations Sandeep Muzumder, Nirmala Srikantia , Ganesha Dev Vashishta , Avinash H. Udayashankar , John Michael Raj , M. G. John Sebastian and Prashanth Bhat Kainthaje
Journal of Radiotherapy in Practice 2018
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Analgesic and Opioid Use in Pain Associated with Head-and-Neck Radiation Therapy

Groups and Associations Sandeep Muzumder, S Nirmala, H U Avinash, Mg John Sebastian, Prashanth Bhat Kainthaje
Indian Journal of Palliative Care 2018
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Immobilization versus no immobilization for pelvic external beam radiotherapy

Groups and Associations Avinash H Udayashankar, Shibina Noorjahan, Nirmala Srikantia, K Ravindra Babu, Sandeep Muzumder
Reports of Practical Oncology & Radiotherapy 2018
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Implication of Bifurcation of Abdominal Aorta for Radiotherapy Planning for Cervical Cancers.

Groups and Associations Ponni TR, Avinash HU, Janaki MG, Koushik AS, Somashekar MK
Journal of Clinical and Diagnostic Research 2015
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A prospective dosimetric and clinical comparison of acute hematological toxicities in three-dimensional conformal radiation therapy and intensity modulated radiation therapy with concurrent chemotherapy in carcinoma cervix

Groups and Associations H U Avinash, T R Arul Ponni, M G Janaki, A S Kirthi Koushik, S Mohan Kumar
Journal of Cancer Research and Therapeutics 2015
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News

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Events

22nd June
Sunday

"Set Right the Setup Errors in Radiotherapy" Draws Technologists from Across India and Abroad

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Announcements

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Schedule

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Speciality Clinics

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