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Projects
Identification and evaluation of prognostic markers involving Rho/ROCK signaling pathway in radiation response in cervical cancer.
Project Description
The study involved assessing the role of ROCK2 as a potential radio-sensitization target for improving radiation response. The classical targeting approach (for knockdown of gene) involves using siRNA to deplete mRNA for the corresponding gene and then understand the phenotype. This approach is very useful in performing in vitro studies to target gene functions in cell lines.
Project Duration
2018 - 2022
Project Lead
Sweta Srivastava
Authors
Sweta Srivastava, Avinash H Udayashankara
Project Status
completed
Project Type
Prospective (Funded by RGUHS)