faculty

Publications

Antihypertensives and Statin Therapy for Primary Stroke Prevention

Groups and Associations Bosch J, Lonn EM, Dagenais GR, Gao P, Jaramillo PL, Zhu J, *Pais P*, Yusuf S ,for the HOPE-3 Investigators
ahajournals 2021

Background and Purpose:

The HOPE-3 trial (Heart Outcomes Prevention Evaluation–3) found that antihypertensive therapy combined with a statin reduced first stroke among people at intermediate cardiovascular risk. We report secondary analyses of stroke outcomes by stroke subtype, predictors, treatment effects in key subgroups.