Faculty & Staff
Ms Apoorva D
M.Sc
PhD student, Department of Molecular Medicine
- Overview
- Projects
- Publications
- Other Contributions
PhD Scholar affiliated with Manipal Academy of Higher Education (MAHE) and currently working on a research project titled “Evaluating the Role of Sex Steroid Hormones in Tumor Progression of Breast Cancer.” My research focuses on understanding the influence of endocrine and intracrine sex steroid hormones on breast cancer progression, with the aim of elucidating hormone-driven mechanisms that contribute to tumor biology and disease heterogeneity.
Qualification/ Education
- M.Sc- St Joseph's University
- B.Sc- St Joseph's University
Experience
Role: Junior Research Fellow
Institute: St John’s Research Institute
Time: February 2023 - present
Role: Research Assistant
Institute: St John’s Research Institute
Time: November 2020 - January 2023
Projects:
- MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
- To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
- To determine the cytotoxic effects of skin care products on Human Dermal Fibroblast Cell lines and biomarker expression analysis by qPCR.
- Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines.
Areas of interest
- Endocrine and intracrine hormonal influence on breast cancer progression.
- microRNA-mediated epigenetic regulation in breast cancer subtypes.
Field of Expertise
- Cell Culture & Functional Assays
- Molecular Biology techniques
- In silico analysis using R and XL-STAT
Fellowship & Membership
CSIR-UGC fellowship (2023-2028)
Role: Junior Research Fellow
Institute: St John’s Research Institute
Time: February 2023 - present
Role: Research Assistant
Institute: St John’s Research Institute
Time: November 2020 - January 2023
Projects:
- MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
- To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
- To determine the cytotoxic effects of skin care products on Human Dermal Fibroblast Cell lines and biomarker expression analysis by qPCR.
- Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines.
- Endocrine and intracrine hormonal influence on breast cancer progression.
- microRNA-mediated epigenetic regulation in breast cancer subtypes.
No groups and associations specified.
No project details available.
Elucidating the Role of MicroRNA-18a in Propelling a Hybrid Epithelial–Mesenchymal Phenotype and Driving Malignant Progression in ER-Negative Breast Cancer – Cells
Madhumathy G. Nair 1, Apoorva D. Mavatkar 1, Chandrakala M. Naidu 1, Snijesh V. P, Anupama C. E. , Savitha Rajarajan , Sarthak Sahoo , Gayathri Mohan , Vishnu Sunil Jaikumar , Rakesh S. Ramesh , Srinath B. S. , Mohit Kumar Jolly , Tessy Thomas Maliekal and Jyothi S. Prabhu An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers – Translational Oncology ,August 2023
Savitha Rajarajana, V.P Snijesha, C.E Anupamaa, Madhumathy G Nair, Apoorva D Mavatkar , Chandrakala M Naidu ,Sharada Patil , Vidya P Nimbalkar , Annie Alexander , Maalavika Pillai , Mohit Kumar Jolly , Radhakrishnan Sabarinathan , Rakesh S Ramesh , Srinath BS , Jyothi S Prabhu Estimation of ALU Repetitive Elements in Plasma as a Cost-Effective Liquid Biopsy Tool for Disease Prognosis in Breast Cancer
Nair MG, Ramesh RS, Naidu CM, Mavatkar AD, V P S, Ramamurthy V, Somashekaraiah VM, C E A, Raghunathan K, Panigrahi A, Das M, Dhar SK, Prabhu JS miR-18a Mediates Immune Evasion in ER-Positive Breast Cancer through Wnt Signaling
Nair MG, D A, M C, Vp S, Patil S, Ce A, Mukherjee G, Kumar RV, Prabhu JS, Ts S No Others Contributions details available.