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Overview
Microbiology
The Microbiology Department began functioning as an Independent Department from 1976. The late Dr. Prema Bhat guided the Department in its initial stages and she was succeeded by Dr. Ragini Macaden, Dr. H Srinivasa, Dr. S Muralidhran and N S Srikanth. The current HOD is Dr. Savitha Nagaraj.
The Department of Microbiology is part of the St. John’s Laboratory services which offers various modalities for diagnosis of infectious diseases. The department comprising of 12 faculty and around 70 laboratory personnel offers a 24/7 diagnostic service. The Laboratory is accredited by National Accreditation Board for Testing and Calibration Laboratories (NABL) since 2007.
We have a dynamic group of microbiologists who strive to provide timely and accurate reports to aid in patient care. Along with the conventional diagnostic techniques, rapid tests and state of the art automated equipment with latest technologies have been incorporated into the laboratory services. Apart from diagnostics, academic and research work forms a major component of the departmental activities. Continual medical education in the form of workshops and conferences are held every year.
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Publications
Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India
Anuja George a, Rosmi Jose a,∗, Chithra Valsan a, Jayanthi Savio b, Priyadarshini A Padaki b, Ramesh Kumar Genomic Insights into the emergence of Carbapenem-Resistant Salmonella Typhi harboring blaNDM-5 in India
T Tharani Priya, Jobin John Jacob, T Monisha Priya, Mahantesh, Bhavana, Suhani, Savitha Nagaraj, Jayanthi Savio, Priyadarshini A Padaki, J Sudarsana, Ashalatha Nair, Suganya Verma, Raman Gaikwad, Divya Joshi, Vasant C Nagvekar, Camilla Rodrigues, S Pavithra, B Santhosh K, Jacob John, Kamini Walia, Balaji Veeraraghavan The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health
Zoe A. Dyson, Louise Cerdeira, Vandana Sharma, Megan E. Carey, Kathryn E. Holt, and the Global Typhoid Genomics Consortium Antimicrobial susceptibility trends of S. Typhi and S. Paratyphi in a post-COVID-19 pandemic India, from a multicenter surveillance network
Sahai N, John Jacob J, Kumar Arunachalam D, Kumar Das B, Kapil A, Pandey S, Dutta S, Chakraborty D, Sen Gupta A, Gupta M, Bansal A, Shah B, Iyer V, Panchal C, Qureshi S, Saigal K, Saikia D, Gupta D, Nagaraj S, Jose S, Thomas M, Mohan S, Veeraraghavan B, Kang G, John J. Seven-day versus 14-day antibiotic course for culture-proven neonatal sepsis: a multicentre randomised non-inferiority trial in a low and middle-income country
Dutta S, Nangia S, Jajoo M, Sundaram M, Kumar M, Shivanna N, Gathwala G, Nesargi S, Jain S, Kumar P, Saili A, Karthik A, Tripathi S, Bandiya P, Dalal P, Ray P, Randhawa VS, Saigal K, Radhakrishnan D, Venkatesh V, Jagannatha B, Sharma M, Nagaraj S, Malik M, Dogra S, Mittal S, Saini A, Makkar N, Dhir M, Chandramohan A, Pragati RA, Srivastava T, Mukundan L, Benakappa N, Shukla A, Rasaily R. Endogenous Endophthalmitis and Subretinal Abscess Following Rituximab Therapy in Myasthenia Gravis: A Report of Two Cases
Thomas S, Rao VP, Nithyanandanam S, Rao V, Shaji D, Nagaraj S, Raju MA Emergence of metronidazole and clindamycin resistance among anaerobic Bacteroides fragilis group - A study from South India
Jacob S, Gachinmath S Influenza vaccination post-COVID-19 expands vaccine-specific effector CD4 T-cells and Tregs under positive influence of host trained innate immunity
Bindhu H, Rakshit S, Adiga V, Ahmed A, Kumar NC, Macrina M, Tripathi H, Vanni F, Montomoli E, Samal S, Raj S. The Development of a Clinical Registry Digital Database on Invasive Fungal Infections in India: Advancing Epidemiological Understanding and Patient Care
Kaur, H., Singh, K. J., Sharma, S., Das, M., Albert, V., Ojha, A. K., Singh, G., Hallur, V., Savio, J., Pamidimukkala, U., Karuna, T., Nath, R., Xess, I., Gupta, P., & Shetty, A Pan-Indian Clinical Registry of Invasive Fungal Infections Among Patients in the Intensive Care Unit: Protocol for a Multicentric Prospective Study
Ojha AK, Albert V, Sharma S, Hallur V, Singh G, Pamidimukkala U, Singh KJ, Kaur H, Karuna T, Savio J, Nath R, Xess I, Gupta P, Shetty A, Das M Risk factors, mortality, and predictors of survival in COVID-19-associated pulmonary mucormycosis: a multicentre retrospective study from India
Muthu V, Agarwal R, Rudramurthy SM, Thangaraju D, Shevkani MR, Patel AK, Shastri PS, Tayade A, Bhandari S, Gella V, Savio J, Madan S, Hallur V, Maturu VN, Srinivasan A, Sethuraman N, Singh Sibia RP, Pujari S, Mehta R, Singhal T, Saxena P, Gupta V, Nagvekar V, Prayag P, Patel D, Xess I, Savaj P, Sehgal IS, Panda N, Rajagopal GD, Parwani RS, Patel K, Deshmukh A, Vyas A, Gandra RR, Sistla SK, Padaki PA, Ramar D, Sarkar S, Rachagulla B, Vallandaramam P, Premachandran KP, Pawar S, Gugale P, Hosamani P, Dutt SN, Nair S, Kalpakkam H, Badhwar S, Kompella KK, Singla N, Navlakhe M, Prayag A, Singh G, Dhakecha P, Chakrabarti A Revised ISHAM-ABPA working group clinical practice guidelines for diagnosing, classifying and treating allergic bronchopulmonary aspergillosis/mycoses
Agarwal R, Sehgal IS, Muthu V, Denning DW, Chakrabarti A, Soundappan K, Garg M, Rudramurthy SM, Dhooria S, Armstrong-James D, Asano K, Gangneux JP, Chotirmall SH, Salzer HJF, Chalmers JD, Godet C, Joest M, Page I, Nair P, Arjun P, Dhar R, Jat KR, Joe G, Krishnaswamy UM, Mathew JL, Maturu VN, Mohan A, Nath A, Patel D, Savio J, Saxena P, Soman R, Thangakunam B, Baxter CG, Bongomin F, Calhoun WJ, Cornely OA, Douglass JA, Kosmidis C, Meis JF, Moss R, Pasqualotto AC, Seidel D, Sprute R, Prasad KT, Aggarwal AN Computed tomography findings of COVID-19-associated pulmonary mucormycosis: Data from a multicenter retrospective study (Mucovi2), India
Muthu V, Agarwal R, Rudramurthy SM, Thangaraju D, Shevkani MR, Patel AK, Shastri PS, Tayade A, Bhandari S, Gella V, Savio J, Madan S, Hallur V, Maturu VN, Srinivasan A, Sethuraman N, Sibia RPS, Pujari S, Mehta R, Singhal T, Saxena P, Gupta V, Nagvekar V, Prayag P, Patel D, Xess I, Savaj P, Sehgal IS, Panda N, Rajagopal GD, Parwani RS, Patel K, Deshmukh A, Vyas A, Gandra RR, Sistla SK, Padaki PA, Ramar D, Panigrahi MK, Sarkar S, Rachagulla B, Vallandaramam P, Premachandran KP, Pawar S, Gugale P, Hosamani P, Dutt SN, Nair S, Kalpakkam H, Badhwar S, Kompella KK, Singla N, Prayag A, Singh G, Dhakecha P, Chakrabarti A. Prevalence of co-existent COVID-19-associated pulmonary aspergillosis (CAPA) and its impact on early mortality in patients with COVID-19-associated pulmonary mucormycosis (CAPM)
Muthu V, Agarwal R, Rudramurthy SM, Thangaraju D, Shevkani MR, Patel AK, Shastri PS, Tayade A, Bhandari S, Gella V, Savio J, Madan S, Hallur V, Maturu VN, Srinivasan A, Sethuraman N, Sibia RPS, Pujari S, Mehta R, Singhal T, Saxena P, Gupta V, Nagvekar V, Prayag P, Patel D, Xess I, Savaj P, Sehgal IS, Panda N, Rajagopal GD, Parwani RS, Patel K, Deshmukh A, Vyas A, Gandra RR, Sistla SK, Padaki PA, Ramar D, Panigrahi MK, Sarkar S, Rachagulla B, Vallandaramam P, Premachandran KP, Pawar S, Gugale P, Hosamani P, Dutt SN, Nair S, Kalpakkam H, Badhwar S, Kompella KK, Singla N, Navlakhe M, Prayag A, Singh G, Dhakecha P, Chakrabarti A Unusual Presentation of Conidiobolomycosis
Jisha MK, Savio J, Muralidharan J, Crasta JA, Padaki PA. Risk factors for recognized and unrecognized SARS-CoV-2 infection: a seroepidemiologic analysis of the Prospective Urban Rural Epidemiology (PURE) study
Leong DP, Loeb M, Mony PK, Rangarajan S, Mushtaha M, Miller MS, Dias M, Yegorov S, V M, Telci Caklili O, Temizhan A, Szuba A, Abat MEM, Mat-Nasir N, Diaz ML, Khansaheb H, Lopez-Jaramillo P, Duong M, Teo KK, Poirier P, Oliveira G, Avezum Á, Yusuf S Traditional versus reverse algorithm for diagnosis of syphilis – An Indian perspective from a national referral laboratory for sexually transmitted infections
Verma S, Panda PS, Muralidhar S, Rajan S, Khunger N. Correlation of severity & clinical outcomes of COVID-19 with virus variants: A prospective, multicentre hospital network study
Wadhwa K, Malik S, Balaji S, Thiruvengadam R, Bashyam MD, Bhattacharya PK, Behera B, Bhardwaj P, Biswas NK, Das A, Dey A, Dhotre D, Dias M, Dubey P, Dutta S, Gadepalli R, Gosain M, Goud KI, Gupta NK, Gupta N, Jana P, Jena D, John E, Karunanidhi A, Khan SMS, Khattar S, Paul APK, Kumar S, Maitra A, Modi N, Moorthy M, Nagaraj S, Palakodeti D, Pandey AK, Pandey A, Raghav SK, Ramasubban S, Raghavan S, Harikrishnan S, Krishnamoorthy S, Selvamurugan S, Sardana R, Shouche Y, Singh A, Singh AK, Ramasubramaniyan V, Yadav M, Zahoor D, Narreddy S, Bhatnagar S, Wadhwa N, Das B, Garg PK. The Silent Pathogen in Pregnancy with Grave Outcome
Christy Vijay, Vishnupriya KM Naga, Priyadarshini A Padaki, Ruchita Chhabra BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections
Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, Sadler C, Slater I, Morton M, Chandrasekaran A, Griffen E. Immune profiling reveals umbilical cord blood mononuclear cells from South India display an IL-8 dominant, CXCL-10 deficient polyfunctional monocyte response to pathogen-associated molecular patterns that is distinct from adult blood cells
Adiga V, Bindhu H, Ahmed A, Chetan Kumar N, Tripathi H, D'Souza G, Dias M, Shivalingaiah S, Rao S, K N S, Hawrylowicz C, Dwarkanath P, Vyakarnam A. Associated Risk Factors and Clinical Outcomes of Bloodstream Infections among COVID-19 Intensive Care Unit Patients in a Tertiary Care Hospital
Shivalingappa MD, Gachinmath S, Narayan SK Role of Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry for Species Identification of Acinetobacter Strains
Krishnaraj A, Gupta P, Bhatia M, Omar BJ Multicenter Case-Control Study of COVID-19-Associated Mucormycosis Outbreak, India
Muthu V, Agarwal R, Rudramurthy SM, Thangaraju D, Shevkani MR, Patel AK, Shastri PS, Tayade A, Bhandari S, Gella V, Savio J, Madan S, Hallur VK, Maturu VN, Srinivasan A, Sethuraman N, Sibia RPS, Pujari S, Mehta R, Singhal T, Saxena P, Gupta V, Nagvekar V, Prayag P, Patel D, Xess I, Savaj P, Panda N, Rajagopal GD, Parwani RS, Patel K, Deshmukh A, Vyas A, Sistla SK, Padaki PA, Ramar D, Sarkar S, Rachagulla B, Vallandaramam P, Premachandran KP, Pawar S, Gugale P, Hosamani P, Dutt SN, Nair S, Kalpakkam H, Badhwar S, Kompella KK, Singla N, Navlakhe M, Prayag A, Singh G, Dhakecha P, Chakrabarti A. Obstetric, Neonatal Outcomes and Histopathological Changes in COVID-positive Pregnancies in a South Indian Population
Vishnupriya Katam Mohini Naga1 , Shashikala Karanth2 , Chandrakala Bada Shekharappa3 , Christy Vijay4 , Gayatri Ravikumar5 , Mamatha6 , Annamma Thomas Polyfunctional CD4 T-cells correlating with neutralising antibody is a hallmark of COVISHIELDTM and COVAXIN® induced immunity in COVID-19 exposed Indians
Rakshit S, Babji S, Parthiban C, Madhavan R, Adiga V, J SE, Chetan Kumar N, Ahmed A, Shivalingaiah S, Shashikumar N, V M, Johnson AR, Ramesh N, B RG, Asokan M, Mayor S, Kang G, D'souza G, Dias M, Vyakarnam A BCG revaccination in adults enhances pro-inflammatory markers of trained immunity along with anti-inflammatory pathways
Ahmed A, Tripathi H, van Meijgaarden KE, Kumar NC, Adiga V, Rakshit S, Parthiban C, Eveline J S, D'Souza G, Dias M, Ottenhoff THM, Netea MG, Joosten SA, Vyakarnam A Genomic analysis unveils genome degradation events and gene flux in the emergence and persistence of S. Paratyphi A lineages
Jacob JJ, Pragasam AK, Vasudevan K, Velmurugan A, Priya Teekaraman M, Priya Thirumoorthy T, Ray P, Gupta M, Kapil A, Bai SP, Nagaraj S. Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes
Carey ME, Dyson ZA, Ingle DJ, Amir A, Aworh MK, Chattaway MA, Chew KL, Crump JA, Feasey NA, Howden BP, Keddy KH, Maes M, Parry CM, Van Puyvelde S, Webb HE, Afolayan AO, Alexander AP, Anandan S, Andrews JR, Ashton PM, Basnyat B, Bavdekar A, Bogoch II, Clemens JD, da Silva KE, De A, de Ligt J, Diaz Guevara PL, Dolecek C, Dutta S, Ehlers MM, Francois Watkins L, Garrett DO, Godbole G, Gordon MA, Greenhill AR, Griffin C, Gupta M, Hendriksen RS, Heyderman RS, Hooda Y, Hormazabal JC, Ikhimiukor OO, Iqbal J, Jacob JJ, Jenkins C, Jinka DR, John J, Kang G, Kanteh A, Kapil A, Karkey A, Kariuki S, Kingsley RA, Koshy RM, Lauer AC, Levine MM, Lingegowda RK, Luby SP, Mackenzie GA, Mashe T, Msefula C, Mutreja A, Nagaraj G, Nagaraj S, Nair S, Naseri TK, Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences
Sankaradoss A, Jagtap S, Nazir J, Moula SE, Modak A, Fialho J, Iyer M, Shastri JS, Dias M, Gadepalli R, Aggarwal A, Vedpathak M, Agrawal S, Pandit A, Nisheetha A, Kumar A, Bordoloi M, Shafi M, Shelar B, Balachandra SS, Damodar T, Masika MM, Mwaura P, Anzala O, Muthumani K, Sowdhamini R, Medigeshi GR, Roy R, Pattabiraman C, Krishna S, Sreekumar E. Evaluation of hospital environment for presence of Mucorales during COVID-19-associated mucormycosis outbreak in India - a multi-centre study
Biswal M, Gupta P, Kanaujia R, Kaur K, Kaur H, Vyas A, Hallur V, Behera B, Padaki P, Savio J, Nagaraj S, Chunchanur SK, Shwetha JV, Ambica R, Nagdeo N, Khuraijam R, Priyolakshmi N, Patel K, Thamke D, Dash L, Jadhav D, Bharmal R, Bhattacharya S, Rudramurthy SM, Chakrabarti A "Effectiveness of a novel, non-intrusive, continuous-use air decontamination technology to reduce microbial contamination in clinical settings: A multi-centric study"
"Nagaraj S, Chandrasingh S, Jose S, B S, Sampath S, Krishna B, Menon I, Kundu D, Parekh S, Madival D, Nandi V, Ghatak A" Isolation of obligate anaerobes from clinical samples received for routine bacterial culture and sensitivity: a cross sectional study
Ayesha BB, Gachinmath S, Sobia C. Interference of Antinuclear Antibody (ANA) in Indirect Immunofluorescence Assay (IIFA)-Based Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA) Interpretation
Deka S, Kalita D, Rekha US, Mahanta P, Rani D, Shankar R, Raj Anusha Krishna, Jha MK, Badoni G, Paul M, Gupta SK, Negi S, Singh A, Chatterjee K Feasibility of Indirect immunofluorescence (IIF) alone as a screening method for antinuclear antibody in connective diseases in India's sub-Himalayan region
Kalita D, Rekha US, Anusha K Raj, Mahanta P, Gupta P, Deka S Antibody to Dense Fine Speckled 70 and its Significance in a Sub-Himalayan Population A Hospital-based Study
Kalita, Deepjyoti; Mangla, Amit; Rekha, U Sashi; Krishnaraj, Anusha; Deka, Sangeeta A simple high-volume culture technique-Good substitute for polymerase chain reaction for the detection of Aspergillus species in bronchoalveolar lavage samples
Haritha Subhagan, Jayanthi Savio, Priyadarshini Padaki, Sweta Srivastava, Pavana Thomas, Rajeshwari Veerappan, Priya Ramachandran, John Michael Raj Ashok Isavuconazole - The new triazole
Savio, Jayanthi Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults
Rakshit S, Adiga V, Ahmed A, Parthiban C, Chetan Kumar N, Dwarkanath P, Shivalingaiah S, Rao S, D'Souza G, Dias M, Maguire TJA, Doores KJ, Zoodsma M, Geckin B, Dasgupta P, Babji S, van Meijgaarden KE, Joosten SA, Ottenhoff THM, Li Y, Netea MG, Stuart KD, De Rosa SC, McElrath MJ, Vyakarnam A Validated In Silico Population Model of Escherichia coli
Rajagopal S, Hmar RV, Mookherjee D, Nagaraj S, Ghatak A, Shanbhag AP, Katagihallimath N, Venkatraman J, Ks R, Datta S Arcanobacterium haemolyticum: A case series
Thomas T, Gachinmath S, Kumari P. Innate Immune Cytokine Profiling and Biomarker Identification for Outcome in Dengue Patients
Pradeep SP, Hoovina Venkatesh P, Manchala NR, Vayal Veedu A, Basavaraju RK, Selvasundari L, Ramakrishna M, Chandrakiran Y, Krishnamurthy V, Holigi S, Thomas T, Ross CR, Dias M, Satchidanandam V The Evolution of Regulatory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype C
Bhange D, Prasad N, Singh S, Prajapati HK, Maurya SP, Gopalan BP, Nadig S, Chaturbhuj D, Jayaseelan B, Dinesha TR, Ahamed SF, Singh N, Brahmaiah A, Mehta K, Gohil Y, Balakrishnan P, Das BK, Dias M, Gangakhedkar R, Mehendale S, Paranjape RS, Saravanan S, Shet A, Solomon SS, Thakar M, Ranga U A century of BCG: Impact on tuberculosis control and beyond
Ahmed A, Rakshit S, Adiga V, Dias M, Dwarkanath P, D'Souza G, Vyakarnam A Molecular detection of virulence markers to identify diarrhoeagenic Escherichia coli isolated from Mula-Mutha river, Pune District, India
Namachivayam SR, Dhawde RR, Macaden RS, Dias M, Birdi TJ. Advancing Fungal Diagnostic and Research Stewardship in India: A Prospective Strategic 10-Step Plan for Addressing a National Public Health Challenge
Madhuchhanda Das, Venencia Albert, Saurabh Sharma, Gagandeep Singh, Vinay Kumar Hallur, Umabala Pamidimukkala, Khangembam Jitenkumar Singh, Tadepalli Karuna, Immaculata Xess, Jayanthi Savio, Reema Nath, Prashant Gupta and Anjali Shetty Textbook of Fungal Zoonoses and Sapronoses
Parija SC, Rudramurthy SM, editors. No Data available for Books.
Basidiobolomycosis caused by a rare species - Basidiobolus meristosporus
Raju S Rajkiran a, Priyadarshini A Padaki b, Hansraj Choudhary c, AM Shubha a, Ruchita Chhabra b, Jayanthi Savio News
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