Projects

Torsemide in the Management of Essential Hypertension

Groups and Associations Kuntal Bhattacharyya 1, Mangesh Tiwaskar , Arnab Datta , Arti Lal Chandani , Santosh Kumar Agrawal , Jabir Abdullakutty , Rajesh Badani , Dhaval Doshi , Vikas Singh , Prashant Advani , Kiron Varghese , Ajay Kumar Pandey , Febin Francis , Amarnath Sugumaran
J Assoc Physicians India . 2024

Torsemide, a loop diuretic, is increasingly recognized for its role in managing essential hypertension. Its mechanism of action involves inhibiting the reabsorption of sodium and chloride ions in the ascending loop of Henle in the kidneys. By doing so, torsemide promotes diuresis, which refers to increased urine production, and subsequently lowers blood pressure. Studies have shown that torsemide is comparably effective to other antihypertensive agents in lowering blood pressure, with the added benefit of potentially improving renal function. However, while torsemide shows promise in hypertensive management, further research is necessary to fully understand its long-term effects and to establish optimal dosing strategies. Future research should focus on clarifying its role in long-term blood pressure control and refining its use in clinical practice to maximize efficacy and minimize adverse effects.

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