Projects

Background: Driver mutation analysis has transformed the treatment landscape of Non Small Cell Lung Cancer (NSCLC), but there exists a significant disparity in the availability of molecular analysis to document the presence of driver mutations and accessibility to the corresponding targeted therapy. The present study sought to explore the clinical and molecular landscape of metastatic NSCLC in an Indian population, looking at the penetrance of molecular testing along with the accessibility and receipt of appropriate targeted therapy. Methods: The present study is a one year retrospective analysis of all patients of metastatic NSCLC who underwent molecular characterisation, by means of NGS hotspot testing or a limited panel. Clinicopathological features and the molecular analysis were collated. The treatment received by the patients were documented, with a focus on the patients who had targetable