Projects

Collision tumors yield two distinct histopathological entities in the same anatomic location and are rarely encountered in routine neuropathology practice. The review of literature has revealed only 33 cases of collision tumor. We aim to report a case of an intracranial collision tumor in a 53-year-old male patient with no prior history or known symptoms of a pre-existing malignancy and who succumbed to the disease. The histopathology revealed both glial and non-glial tumor: Isocitrate dehydrogenase-mutant astrocytoma (World Health Organization Grade 4) and metastatic adenocarcinoma. The lack of awareness and resources in rural patients regarding symptomatology of cancers can lead to reduced index of suspicion for pre-existing malignancies. This case highlights the need for adequate pre-operative systemic and radiological examination and meticulous histopathological evaluation for accurate diagnosis and management.