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Projects
Evaluation and validation of four scoring systems: the apache IV, saps III, MPM0 II, and ICMM in critically ill cancer patients
Siddiqui, Suhail S; Narkhede, Amit M; Kulkarni, Atul P; Prabu, Natesh R; Chaudhari, Harish K; Sarode, Satish V; Divatia, Jigeeshu V; Abstract
Background and aims: To evaluate and validate four severity-of-illness scores, acute physiology and chronic health evaluation IV (APACHE IV), simplified acute physiology score III (SAPS III), mortality probability models II at 0 hours (MPM0 II), and ICU cancer mortality model (ICMM), in a prospective cohort of critically ill cancer patients.
Materials and methods: Single-center, prospective observational study performed in a 14-bedded combined medical-surgical ICU of a tertiary care cancer center of India, from July 2014 to November 2015. Score performance was judged by discrimination and calibration, using the area under receiver-operating characteristics (ROC) curve and Hosmer-Lemeshow goodness-of-fit test, respectively.