Projects

Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes

Groups and Associations Ann Riya Jacob, Jerry Paul, Sunil Rajan, Greeshma C. Ravindran, Lakshmi Kumar
Anesthesia: Essays and Researches 2022

Background and Aims: Spinal anesthesia is a technique widely used for gynecological, lower abdominal, pelvic and lower limb procedures.
Even though it causes a profound nerve block, it is associated with profound hypotension. Aims of the Study: To assess the effect of the speed
of injection of heavy bupivacaine on quality of block and hemodynamic changes in patients undergoing gynecological surgeries under spinal
anesthesia. Methods: This was a prospective randomized study conducted on 40 patients. Group F patients were given 3.2 mL of 0.5% heavy
bupivacaine intrathecally in 15 s and Group S patients were given the same drug over 60 s. The time to achieve T10 dermatomal block, maximum
block height, block height at 5 min were recorded. Heart rate (HR), systolic, diastolic blood pressures, and mean arterial pressures (MAP) were
also recorded at different time points. Results: HR, systolic BP, diastolic BP, and MAPs and mean block height at 5 min were comparable
between the two groups at all time points. The time to achieve T10 dermatome block was significantly faster in Group F (1.85 ± 1.14 min) as
compared to Group S (3.98 ± 1.58 min). Majority of patients in Group F (65%) had a maximum block up to T6 and those in Group S (45%)
had a block upto T4. The usage of vasopressors was found to be significantly higher in Group F compared to Group S with P = 0.041.
Conclusion: Using faster speed of injection of heavy bupivacaine during spinal anesthesia can lead to faster achievement of blockade but
with significantly higher usage of vasopressors.
Keywords: Anesthesia, bupivacaine, speed, spina

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