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Demographics and clinical characteristics of COVID-19-vaccinated patients admitted to ICU: a multicenter cohort study from India (Postcovac study-COVID group)
Amarja Ashok Havaldar 1, Jay Prakash 2, Sanjeev Kumar 3, Kaladhar Sheshala 4, Abhilash Chennabasappa 5, Ria Rachel Thomas 1, Ea Chinny Sushmitha 1, Mohd Saif Khan 2, Raman Kumar 6, Srishti Kindo 6, Ritu Singh 7, Munta Kartik 4, Akshay Hiruyur Manjunatha Swamy 8, John Michael Raj 9, Tinku Thomas 9, Sumithra Selvam 10 Abstract
Background: Emergency authorization and approval were given for the coronavirus disease-19 (COVID-19) vaccines. The efficacy reported after phase III trials were 70.4% and 78% for Covishield and Covaxin, respectively.In this study, we aim to analyze the risk factors, which were associated with mortality in critically ill COVID-19-vaccinated patients admitted into intensive care unit (ICU).
Materials and methods: This study was conducted from April 1, 2021 to December 31, 2021 across five centers in India. Patients who had received either one or two doses of any of the COVID vaccines and developed COVID-19 were included. The ICU mortality was a primary outcome.