Projects

In clinical medicine, multicenter collaborative research usually leads to a large pool of data that are considered nearer to real-world representativeness by the expert in their respective fields. Collaborative research in critical care medicine holds immense promise in advancing our comprehension of critical illnesses, leading to improved patient care and, ultimately, saving lives.

In recent years, countable numbers of high-impact research publications have started to appear in the field of critical care medicine from India. Some of them are landmark studies like a study on treatment strategy for severe scrub typhus and another on the burden of typhoid and paratyphoid fever in India, both original studies were published in 2023 in the New England Journal of Medicine.1,2 A randomized control trial (RCT) on tocilizumab for moderate-severe COVID-19 was published in the Lancet Respiratory Medicine (2021), while an important observational study on healthcare-associated bloodstream and urinary tract infections from multiple Indian ICUs was published in the Lancet Global Health (2022).3,4 There were some other high-impact publications in the Journal of American Medical Association in which Indian centers participated as international collaborators, like the use of red blood cell transfusion in the ICU (2023), evaluating different doses of dexamethasone for COVID-19 (2021), intubation practices and peri-intubation adverse events (2021).5–7 Epidemiology, management and outcome of sepsis in ICUs across Asia was published in the American Journal of Respiratory and Critical Care Medicine (2022), and epidemiology of ICU acquired bloodstream infection was published in Intensive Care Medicine (2023).8,9