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Clinicopathological Profile of CMV Colitis at a Tertiary Care Center

Groups and Associations Dr. Renuka Malipatel 2. Dr. Mallikarjun Patil
National Journal of Laboratory Medicine. 2018

Abstract

Introduction: Cytomegalovirus (CMV) infection is commonly seen in immunosuppressed individuals like Acquired Immunodeficiency Syndrome (AIDS), receiving chemotherapy/other immunosuppressive drugs, Inflammatory Bowel Disease (IBD). Rarely seen in immunocompetent individuals; CMV can involve any part of gastrointestinal tract, but commonly involves the colon. Aim: To study the clinicopathological features of CMV colitis at St John's Medical College. Materials and Methods: A retrospective study involving all CMV colitis patients admitted in the hospital from January 2010 to December 2017 was conducted. All histopathologically proven cases of CMV colitis were included. From the hospital records clinical, demographic and serological data were retrieved. Histopathology slides were reviewed. Results: Eighteen patients with CMV colitis were studied. Mean age was 57 years (range 32-86). The underlying predisposing factors like AIDS, post organ transplant, IBD were seen in 10 patients. Ei...

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