Projects

Understanding the role of ER- mito interaction in radiation resistance cervical and Breast cancer cells

Project Description

The Mitochondrial Associated Membrane (MAM) forms through the tethering of the endoplasmic reticulum to the mitochondrial membrane. Under stress conditions such as radiation, mitochondrial function becomes impaired, prompting the recruitment of endoplasmic reticulum proteins for cell survival. Therefore, understanding the role of ER and mitochondria interactions is crucial for the development of inhibitors or drugs to sensitize cancer cells to radiation.

Project Duration

2021 - 2026

Project Lead

Dr Harini L

Authors

Dr Harini L

Project Status

ongoing

Project Type

ICMR- DHR Women Scientist Scheme

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