Projects

Project Description

Chronic kidney disease is defined by presence of kidney damage (structural or functional abnormality involving pathological, laboratory or imaging findings) for ≥ 3 months or a GFR < 60 ml/min/1.73 m2 for ≥ 3 months1. Nutritional status is particularly important in children, because it influences growth, sexual development, and neurocognitive development2.Adverse changes in nutrition, contributing to morbidity and mortality, is highly prevalent in children with chronic kidney disease. In the context of CKD, the term protein-energy wasting (PEW) has been proposed by The International Society of Renal Nutrition and Metabolism (ISRNM) to describe a “state of decreased body stores of protein and energy fuels (body protein and fat masses)”1 and recommended a criteria for a diagnosis of PEW in adults.3 This was further modified for children4 and comprised of into five distinct criteria: a. biochemical indicators; b. low body weight, reduced body fat, or weight loss; c. decreased muscle mass; d. low protein or energy intake and e. Height velocity or short stature.